CHOLINOMIMETIC EFFECTS OF AQUEOUS EXTRACTS FROM Carum copticum SEEDS

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Effects of the Persian Carum copticum fruit extracts on morphine withdrawal syndrome in mice

Carum copticum from Apiaceae family has several biological effects including analgesic, anti-inflammatory, anxiolytic and antispasmodic activities. This study was designed to evaluate its effect on suppression of naloxone-induced morphine withdrawal signs. Hydroalcoholic and polyphenolic extracts were prepared according to the standard methods. Male mice (25-30 g) were made dependent by subcuta...

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Carum copticum L.: A Herbal Medicine with Various Pharmacological Effects

Carum copticum L. commonly known as "Ajwain" is cultivated in many regions of the world including Iran and India, states of Gujarat and Rajasthan. Traditionally, C. copticum has been used in the past for various therapeutic effects including bloating, fatigue, diarrhea, abdominal tumors, abdominal pain, respiratory distress, and loss of appetite. It has other health benefits such as antifungal,...

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Bronchodilatory effect of Carum copticum in airways of asthmatic patients.

BACKGROUND Several therapeutic effects including anti-asthma and dyspnea have been described for the seeds of Carum copticum. In previous studies the relaxant and anticholinergic (functional antagonism) effects, histamine H(1) inhibitory and beta(2) stimulatory effects of Carum copticum have been demonstrated on guinea pig tracheal chains. In the present study, the bronchodilatory effect of boi...

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ژورنال

عنوان ژورنال: British Journal of Pharmacology

سال: 1974

ISSN: 0007-1188

DOI: 10.1111/j.1476-5381.1974.tb09732.x